ChloroquineV1, Main, Exploration, bibRecord, 003A29

Tumor‐ and Drug‐Induced Cutaneous Neuro‐Phospholipidosis

Identifieur interne : 003A29 ( Main/Exploration ); précédent : 003A28; suivant : 003A30

Tumor‐ and Drug‐Induced Cutaneous Neuro‐Phospholipidosis

Auteurs : C. E. Orfanos [Allemagne] ; U. Runne [Allemagne]

Source :

Journal of Cutaneous Pathology [ 0303-6987 ] ; 1975-10.

RBID : ISTEX:0CB9F6230B9CA009395D699CED966AC15B294C71

Descripteurs français

KwdFr :
- Adulte, Adulte d'âge moyen, Analgésiques (effets indésirables), Analgésiques (usage thérapeutique), Axones (ultrastructure), Carcinome bronchogénique (), Carcinome bronchogénique (anatomopathologie), Chloroquine (effets indésirables), Chloroquine (usage thérapeutique), Ergotamine (effets indésirables), Ergotamine (usage thérapeutique), Femelle, Humains, Lipidoses (), Lipidoses (étiologie), Mâle, Mélanome (anatomopathologie), Métastase tumorale, Neuropathies périphériques (), Neuropathies périphériques (étiologie), Peau (innervation), Phospholipides (métabolisme), Sujet âgé, Tumeurs cutanées (), Tumeurs cutanées (anatomopathologie), Tumeurs du poumon (), Tumeurs du poumon (anatomopathologie).
MESH :
- anatomopathologie : Carcinome bronchogénique, Mélanome, Tumeurs cutanées, Tumeurs du poumon.
- effets indésirables : Analgésiques, Chloroquine, Ergotamine.
- métabolisme : Peau, Phospholipides.
- usage thérapeutique : Analgésiques, Axones, Chloroquine, Ergotamine.
- étiologie : Lipidoses, Neuropathies périphériques.
- Adulte, Adulte d'âge moyen, Carcinome bronchogénique, Femelle, Humains, Lipidoses, Mâle, Métastase tumorale, Neuropathies périphériques, Sujet âgé, Tumeurs cutanées, Tumeurs du poumon.

English descriptors

KwdEn :
- Adult, Aged, Analgesics (adverse effects), Analgesics (therapeutic use), Axons (ultrastructure), Carcinoma, Bronchogenic (complications), Carcinoma, Bronchogenic (pathology), Chloroquine (adverse effects), Chloroquine (therapeutic use), Ergotamine (adverse effects), Ergotamine (therapeutic use), Female, Humans, Lipidoses (chemically induced), Lipidoses (etiology), Lung Neoplasms (complications), Lung Neoplasms (pathology), Male, Melanoma (pathology), Middle Aged, Neoplasm Metastasis, Peripheral Nervous System Diseases (chemically induced), Peripheral Nervous System Diseases (etiology), Phospholipids (metabolism), Skin (innervation), Skin Neoplasms (complications), Skin Neoplasms (pathology).
MESH :
- chemical , adverse effects : Analgesics, Chloroquine, Ergotamine.
- chemical , metabolism : Phospholipids.
- chemical , therapeutic use : Analgesics, Chloroquine, Ergotamine.
- chemically induced : Lipidoses, Peripheral Nervous System Diseases.
- complications : Carcinoma, Bronchogenic, Lung Neoplasms, Skin Neoplasms.
- etiology : Lipidoses, Peripheral Nervous System Diseases.
- innervation : Skin.
- pathology : Carcinoma, Bronchogenic, Lung Neoplasms, Melanoma, Skin Neoplasms.
- ultrastructure : Axons.
Teeft :
- Abraham hendy, Adult, Aged, Axon, Axonal, Barbituric acid, Brain gangliosides, Bronchogenic carcinoma, Carcinoma, Carcinomatous, Carcinomatous neuropathy, Chloroquine, Chronic abuse, Cutaneous, Cutaneous axons, Drug history, Electron microscope, Female, Hereditary disorders, Humans, Jottrnal, Lipid, Lipid storage, Male, Middle Aged, Neoplasm Metastasis, Neuromyopathy, Neuropathy, Orfanos, Peripheral neuromyopathy, Runne, Schwann cells.

Abstract

Drugs and metastatic malignant tumors may induce severe alterations in cutaneous axons. The most prominent ultrastructural feature of axonal dystrophy of this type was the presence of multiple lamellated osmiophilic bodies (LOB), similar to those occurring in hereditary disorders with increase of brain gangliosides and lipid storage. Chloroquine, ergotamine, ethaverine and chronic abuse of non‐narcotic analgesic drugs seem to be responsible for the drug‐induced cutaneous neuro‐phospholipidosis, whereas the same condition was found in two patients with metastatic bronchogenic carcinoma and malignant melanoma.

Url:

https://api.istex.fr/ark:/67375/WNG-ZPNF9GK3-9/fulltext.pdf

DOI: 10.1111/j.1600-0560.1975.tb00171.x

Affiliations:

Allemagne

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Analgesics (adverse effects)</term>
<term>Analgesics (therapeutic use)</term>
<term>Axons (ultrastructure)</term>
<term>Carcinoma, Bronchogenic (complications)</term>
<term>Carcinoma, Bronchogenic (pathology)</term>
<term>Chloroquine (adverse effects)</term>
<term>Chloroquine (therapeutic use)</term>
<term>Ergotamine (adverse effects)</term>
<term>Ergotamine (therapeutic use)</term>
<term>Female</term>
<term>Humans</term>
<term>Lipidoses (chemically induced)</term>
<term>Lipidoses (etiology)</term>
<term>Lung Neoplasms (complications)</term>
<term>Lung Neoplasms (pathology)</term>
<term>Male</term>
<term>Melanoma (pathology)</term>
<term>Middle Aged</term>
<term>Neoplasm Metastasis</term>
<term>Peripheral Nervous System Diseases (chemically induced)</term>
<term>Peripheral Nervous System Diseases (etiology)</term>
<term>Phospholipids (metabolism)</term>
<term>Skin (innervation)</term>
<term>Skin Neoplasms (complications)</term>
<term>Skin Neoplasms (pathology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analgésiques (effets indésirables)</term>
<term>Analgésiques (usage thérapeutique)</term>
<term>Axones (ultrastructure)</term>
<term>Carcinome bronchogénique ()</term>
<term>Carcinome bronchogénique (anatomopathologie)</term>
<term>Chloroquine (effets indésirables)</term>
<term>Chloroquine (usage thérapeutique)</term>
<term>Ergotamine (effets indésirables)</term>
<term>Ergotamine (usage thérapeutique)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lipidoses ()</term>
<term>Lipidoses (étiologie)</term>
<term>Mâle</term>
<term>Mélanome (anatomopathologie)</term>
<term>Métastase tumorale</term>
<term>Neuropathies périphériques ()</term>
<term>Neuropathies périphériques (étiologie)</term>
<term>Peau (innervation)</term>
<term>Phospholipides (métabolisme)</term>
<term>Sujet âgé</term>
<term>Tumeurs cutanées ()</term>
<term>Tumeurs cutanées (anatomopathologie)</term>
<term>Tumeurs du poumon ()</term>
<term>Tumeurs du poumon (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Analgesics</term>
<term>Chloroquine</term>
<term>Ergotamine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Phospholipids</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Analgesics</term>
<term>Chloroquine</term>
<term>Ergotamine</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome bronchogénique</term>
<term>Mélanome</term>
<term>Tumeurs cutanées</term>
<term>Tumeurs du poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Lipidoses</term>
<term>Peripheral Nervous System Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Carcinoma, Bronchogenic</term>
<term>Lung Neoplasms</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Analgésiques</term>
<term>Chloroquine</term>
<term>Ergotamine</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lipidoses</term>
<term>Peripheral Nervous System Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="innervation" xml:lang="en"><term>Skin</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Peau</term>
<term>Phospholipides</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Carcinoma, Bronchogenic</term>
<term>Lung Neoplasms</term>
<term>Melanoma</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Axons</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Analgésiques</term>
<term>Axones</term>
<term>Chloroquine</term>
<term>Ergotamine</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lipidoses</term>
<term>Neuropathies périphériques</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en"><term>Abraham hendy</term>
<term>Adult</term>
<term>Aged</term>
<term>Axon</term>
<term>Axonal</term>
<term>Barbituric acid</term>
<term>Brain gangliosides</term>
<term>Bronchogenic carcinoma</term>
<term>Carcinoma</term>
<term>Carcinomatous</term>
<term>Carcinomatous neuropathy</term>
<term>Chloroquine</term>
<term>Chronic abuse</term>
<term>Cutaneous</term>
<term>Cutaneous axons</term>
<term>Drug history</term>
<term>Electron microscope</term>
<term>Female</term>
<term>Hereditary disorders</term>
<term>Humans</term>
<term>Jottrnal</term>
<term>Lipid</term>
<term>Lipid storage</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Metastasis</term>
<term>Neuromyopathy</term>
<term>Neuropathy</term>
<term>Orfanos</term>
<term>Peripheral neuromyopathy</term>
<term>Runne</term>
<term>Schwann cells</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Carcinome bronchogénique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lipidoses</term>
<term>Mâle</term>
<term>Métastase tumorale</term>
<term>Neuropathies périphériques</term>
<term>Sujet âgé</term>
<term>Tumeurs cutanées</term>
<term>Tumeurs du poumon</term>
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<front><div type="abstract" xml:lang="en">Drugs and metastatic malignant tumors may induce severe alterations in cutaneous axons. The most prominent ultrastructural feature of axonal dystrophy of this type was the presence of multiple lamellated osmiophilic bodies (LOB), similar to those occurring in hereditary disorders with increase of brain gangliosides and lipid storage. Chloroquine, ergotamine, ethaverine and chronic abuse of non‐narcotic analgesic drugs seem to be responsible for the drug‐induced cutaneous neuro‐phospholipidosis, whereas the same condition was found in two patients with metastatic bronchogenic carcinoma and malignant melanoma.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
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<tree><country name="Allemagne"><noRegion><name sortKey="Orfanos, C E" sort="Orfanos, C E" uniqKey="Orfanos C" first="C. E." last="Orfanos">C. E. Orfanos</name>
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Serveur d'exploration Chloroquine

Tumor‐ and Drug‐Induced Cutaneous Neuro‐Phospholipidosis

Tumor‐ and Drug‐Induced Cutaneous Neuro‐Phospholipidosis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

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